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Project MRSA CO: Prevalence molecular epidemiology and risk for human health of MRSA and other methicillin resistant staphylococci in animals and their owners

Duration of the project

Starting date: 01/05/2008
Ending date: 30/04/2012

Operational Direction

Bacterial Diseases

ROLE OF CODA-CERVA in this project

Coordinator

PRESENTATION

The general objectives of the research are to examine if methicillin-resistance in staphylococci (S. aureus and other staphylococci) from animals represents a potential problem for human beings (risk identification), while analysing specific factors causing risk that MRSA are transferred from animals to humans.

 

This project features three major scientific components.

First and foremost, there is a more epidemiological part, where staphylococci are isolated from the noses of cattle, pigs and poultry and their owners, as well as the carcasses of animals originating from these holdings. Therefore, methods are developed to isolate non-aureus methicillin-resistant staphylococci. The sensitivity of these strains to other antibiotics is determined.

 

A second component involves molecular and biochemical tests for the identification and genetic characterising (PFGE, spa typing, MLST) of staphylococci as well as their methicillin-resistance region (PCR and sequence methods).

 

The third part consists of investigating various factors that may contribute to methicillin-resistant staphylococci being transferred from animals to human beings.

GENERAL INFORMATION

- Scientist responsible for this project

- Team

- External partners

- Source of funding