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Naturally-occuring compounds


Naturally-occurring compoundsMany living organisms are able to produce natural substances with highly-diverse chemical characteristics, and with very varied toxicological and nutritional properties.


Thus, some chemical compounds produced by plants can be toxic in the short or long term, while still possessing medicinal qualities that are useful for health (for example, alkaloids).


Other groups of substances such as glucosinolates may be undesirable in certain situations (for example in the rape used in animal feeds), but beneficial in other cases (e.g. anticarcinogenic properties attributed to certain vegetables such as broccoli).


Lastly, a third group of substances known as polyphenols is universally beneficial to the health, even though in some cases (for example, certain high-risk groups) excessive consumption can result in health problems (for example, phytoestrogens).


CODA-CERVA has many years' experience in analysing highly diverse natural substances of plant origins, such as polyphenols, alkaloids and glucosinolates.

High-performance analytical tools (UPLC-MS/MS) and expertise in synthetic pathways and in describing the various forms present in vegetables (aglycons and glycosylated forms) are great strengths that enable researchers to take part in research work and to provide services for many different clients.


A method has been worked out with a view to being able to determine by UPLC-MS/MS the main molecules of interest (for example: genistein, daidzein, the active ingredients in Ginkgo biloba, Maca alkaloids) present in plant-based products and food supplements. Naturally-occurring compounds

Analyses can be performed by request (contact : A. Callebaut )


CODA-CERVA is involved in a number of research projects dealing with the presence of beneficial or unwanted natural compounds in food supplements (FOODINTER project), also in animal feeds and brassicaceæ (OFFQ project).


Alfons Callebaut
Karine Vandermeiren



- N. Terahara, A. Callebaut, R. Ohba, T. Nagata, M. Ohnishi-Kameyama and M. Suzuki
PHYTOCHEMISTRY 58 (1) 493-500 (2001)
Acylated anthocyanidin 3-sophoroside-5-glucosides from Ajuga reptans flowers and the corresponding cell cultures.


- A. Callebaut, N. Terahara and M. Decleire
PLANT SCIENCE 118, 109-118 (1996)
Anthocyanin acyltransferases in cell cultures of Ajuga reptans.
- N. Terahara, A. Callebaut, R. Ohba, T. Nagata, M. Ohnishi-Kameyama and M. Suzuki
PHYTOCHEMISTRY 42 (1) 199-203 (1996)
Triacylated anthocyanins from Ajuga reptans flowers and cell cultures.


- A. Callebaut, M. Decleire and K. Vandermeiren
in "BIOTECHNOLOGY IN AGRICULTURE AND FORESTRY, VOLUME 24 : MEDICI¬NAL AND AROMATIC PLANTS V", 1-22 (1993). Editor : Y.P.S. Bajaj. Spinger Verlag Berlin Heidelberg.
Ajuga reptans (Bugle) : In Vitro Production of Anthocyanins